Clone, synchronize, backup. Schedule and forget it. Try it ’til you trust it.
The key to a successful backup plan is to actually do the backups regularly. When left to a human, the task often gets tacked on to the end of a very long list of other things to do. When you eventually have a catastrophe, the data is simply gone. You know that feeling — you just lost six years of family photos. Your kids being born, their first birthdays, their first everything. The answer to this is consistent and regular backups, placed on a schedule and handled automatically by your computer.